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Good morning. This is my last newsletter this year. Meghana will be writing the one tomorrow, and then we will be off for the next two weeks. Wishing everyone happy holidays and I’ll see you in the new year.

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Vertex pain drug disappoints in sciatica study

Vertex Pharmaceuticals said this morning that its closely watched drug, suzetrigine, reduced pain compared to baseline but did not outperform a placebo in a Phase 2 study, raising doubts about the medicine’s potential in the lucrative market for treating chronic pain.

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