The headquarter of US biopharmaceutical company Vertex Pharmaceuticals with its logo sign— coverage from STAT
JOSEPH PREZIOSO/AFP via Getty Images

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The need-to-know this morning

  • Bristol Myers Squibb said that Sotyktu, which is already approved to treat plaque psoriasis, met the primary endpoint in two Phase 3 trials of patients with psoriatic arthritis.

What to expect after Novo’s CagriSema readout

CagriSema, Novo Nordisk’s next-gen obesity drug that combines semaglutide with the amylin analog cagrilintide, fell short of weight loss projections — leading to an 18% drop in Novo’s stock. Specifically, the drug promoted weight loss of about 20%, significantly below the 25% weight loss target the company had projected.

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